Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The major pharmacokinetic parameters of DTX solution and DTX-S-LA/DSPE2K NPs.
| Formulations | Determined | Cmax (nmol/mL) | Tmax (h) | AUC0–24 (nmol h/mL) | t1/2 (h) |
|---|---|---|---|---|---|
| DTX solution | DTX | 0.7±0.1 | 0.17±0.0 | 0.7±0.1 | 3.1±1.3 |
| DTX-S-LA/DSPE2K NPs | DTX | 1.5±0.7 | 0.3±0.2 | 2.8±0.95 | 3.2±0.9 |
| DTX-S-LA | 66.6±19.7 | 0.2±0.15 | 65.5±27.7 | 4.0±1.5 |
