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. 2019 Mar 27;63(4):e02061-18. doi: 10.1128/AAC.02061-18

TABLE 2.

Kinetic parameters of C. parvum MetRS compared to MetRS enzymes from other organisms

MetRS Met
ATP
Source or reference
Km (μM) kcat (S−1) kcat/Km (μM−1 S−1) Km (μM) kcat (S−1) kcat/Km (μM−1 S−1)
C. parvum 71 37 0.52 1,040 33 0.03 This study
S. aureus 77 36 0.47 347 26 0.07 This study
S. aureus 100 25 0.25 500 25 0.05 31
Human mitochondria 18 0.41 0.023 85 0.033 0.00038 55