Simulations of gentamicin peak concentrations (A) and trough concentrations (B) for 1,000 virtual patients with all median characteristics of the population but five different dosing schedules (white, 1.5 mg q8h; gray, 4 mg q24h; red, 5 mg q24h; blue, 6 mg q24h; green, 7 mg q24h) and three CLCR levels (10th percentile, 31 ml/min; median, 74 ml/min; and 90th percentile, 119 ml/min).