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Simulations (n = 1,000) of the exposure, namely, AUC (left) and Cmax (right), stratified by body weight after administration of a single oral dose of 400 mg tribendimidine. The dashed horizontal lines indicate the AUC criterion (left) and the Cmax criterion (right) associated with the 90% probability of achieving a cure. The AUC criterion is 4,520 ng·h/ml, and the Cmax criterion is 384 ng/ml. The box and whiskers represent 25th to 75th and 10th to 90th percentiles, respectively.
