Percentage of isolates of Enterobacteriaceae collected in 2012 to 2015 that were multidrug-resistant, by Latin American country. “Multidrug resistant” (MDR) isolates were defined as resistant, according to 2016 CLSI criteria, to three or more sentinel antimicrobial agents from different classes. The green font indicates that <20% of isolates were MDR, the orange font indicates that 20% to 29.9% of isolates were MDR, and the red font indicates that ≥30% of isolates were MDR. ARG, Argentina; BRA, Brazil; CHL, Chile; COL, Colombia; MEX, Mexico; VEN, Venezuela.