TABLE 2.
MICs of all MCM-resistant isolates
| Species | ESBL status (no. of isolates) | MIC (mg/liter) for:a |
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCM | AMP | TZP | CXM | CTX | CAZ | FEP | MER | EPM | CIP | CTM | FOF | GEN | ||
| E. coli | Positive (3) | 64 | ≥32 | ≤4 | ≥64 | ≥64 | 4 | 8 | ≤0.25 | ≤0.5 | ≥4 | ≤1 | ≤16 | ≤1 |
| ≥256 | ≥32 | ≥128 | ≥64 | ≥64 | ≥64 | 32 | ≤0.25 | ≤0.5 | ≥4 | ≥16 | ≤16 | ≤1 | ||
| ≥256 | ≥32 | 64 | ≥64 | ≥64 | 4 | 4 | ≤0.25 | ≤0.5 | ≥4 | ≤1 | ≤16 | ≤1 | ||
| Negative (5) | 128 | ≥32 | 64 | 16 | ≤1 | ≤1 | ≤1 | ≤0.25 | ≤0.5 | ≤0.25 | ≤1 | ≤16 | ≤1 | |
| ≥256 | ≥32 | 64 | 16 | ≤1 | ≤1 | ≤1 | ≤0.25 | ≤0.5 | ≤0.25 | ≤1 | ≤16 | ≤1 | ||
| 32 | ≥32 | ≤4 | 4 | ≤1 | ≤1 | ≤1 | ≤0.25 | ≤0.5 | ≤0.25 | ≥16 | ≤16 | ≤1 | ||
| 32 | ≥32 | ≥128 | 4 | ≤1 | ≤1 | ≤1 | ≤0.25 | ≤0.5 | ≤0.25 | ≥16 | ≤16 | ≤1 | ||
| ≥256 | ≥32 | ≥128 | 8 | ≤1 | ≤1 | ≤1 | ≤0.25 | ≤0.5 | 0.5 | ≤1 | ≤16 | ≤1 | ||
| K. pneumoniae | Positive (1) | 16 | ≥32 | ≤4 | ≥64 | ≥16 | 2 | 2 | ≤0.25 | ≤0.5 | ≥4 | ≥16 | ≤16 | ≤1 |
| Negative (2) | 64 | 8 | 2 | ≤1 | ≤1 | ≤1 | ≤0.25 | ≤0.5 | ≤0.25 | ≤1 | ≤16 | ≤1 | ||
| ≥256 | ≤4 | 2 | ≤1 | ≤1 | ≤1 | ≤0.25 | ≤0.5 | ≤0.25 | ≤1 | ≤16 | ≤1 | |||
| Klebsiella oxytoca | Positive (1) | 128 | ≥32 | ≥128 | ≥64 | 8 | 4 | 2 | ≤0.25 | ≤0.5 | 2 | ≤1 | ≤16 | ≥16 |
| Negative (2) | ≥256 | ≤4 | ≤1 | ≤1 | ≤1 | ≤1 | ≤0.25 | ≤0.5 | ≤0.25 | ≤1 | ≤16 | ≤1 | ||
| 32 | ≤4 | ≤1 | ≤1 | ≤1 | ≤1 | ≤0.25 | ≤0.5 | ≤0.25 | ≤1 | ≤16 | ≤1 | |||
| P. mirabilis | Negative (2) | ≥256 | ≥32 | ≤4 | ≤1 | ≤1 | ≤1 | ≤1 | ≤0.25 | ≤0.5 | ≤0.25 | ≥16 | ≤16 | ≤1 |
| 128 | ≥32 | ≤4 | ≤1 | ≤1 | ≤1 | ≤1 | ≤0.25 | ≤0.5 | 1 | ≥16 | ≤16 | ≥16 | ||
a
AMP, ampicillin; TZP, piperacillin-tazobactam; CXM, cefuroxime; CTX, cefotaxime; CAZ, ceftazidime; FEP, cefepime; MER, meropenem; EPM, ertapenem; CIP, ciprofloxacin; CTM, co-trimoxazole; FOF, fosfomycin; GEN, gentamicin.