FIG 2.

Average daptomycin MIC for VREfm initial isolates by quarter. Open circles are calculated from original clinical MICs, and closed circles are calculated from corrected values. Means prior to February 2015 are only shown as original values, as a correction for these values was not required. Error bars represent 95% confidence interval (CI) of the mean, and the numbers are the number of infections in each quarter. The gray circles show each initial isolate per patient as susceptible or nonsusceptible. Gray line is a local polynomial regression (LOESS) of the daptomycin susceptibility of initial isolates, showing the moving average of the proportion of initial isolates that are daptomycin nonsusceptible. Highlighted panel indicates the study intervention period.