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Observed meropenem (top) and nacubactam (bottom) ELF concentrations in the neutropenic lung infection model, compared with human ELF profiles of meropenem (2 g every 8 h, as 1.5-h infusion) and nacubactam (2 g every 8 h, as 1.5-h infusion). Data are presented as mean ± standard deviation.
