Figure 2.
Cytotoxicity of Y6 in HEK293/pcDNA3.1 and HEK293/ABCB1 cell lines. (A) Cytotoxicity of Y6 was evaluated in pair of parental and MDR cell lines: HEK293/pcDNA3.1 and HEK293/ABCB1. (B) and (C)The concentration–response curves of HEK293/pcDNA3.1 and HEK293/ABCB1 treated with doxorubicin alone and doxorubicin combined with verapamil, EGCG, or Y6. Points with error bars represent the mean ± SD. Three independent experiments were performed in triplicate.