Table 2.

Clinical Outcomes among Women Who Received Medical Treatment for Early Pregnancy Loss.

Outcome	Mifepristone-Pretreatment Group (N = 148)	Misoprostol-Alone Group (N = 149)	Relative Risk (95% CI)*
	number (percent)
Gestational sac expulsion by the first follow-up visit: treatment success†	124 (83.8)	100 (67.1)	1.25 (1.09–1.43)‡
Gestational sac expulsion by the second follow-up visit at day 8	132 (89.2)	111 (74.5)	1.20 (1.07–1.33)
With 1 dose of misoprostol	130 (87.8)	106 (71.1)
With 2 doses of misoprostol	2 (1.4)	5 (3.4)
Gestational sac expulsion by the 30-day telephone call	135 (91.2)	113 (75.8)	1.20 (1.08–1.33)
With 1 dose of misoprostol	130 (87.8)	106 (71.1)
With 2 doses of misoprostol	5 (3.4)	7 (4.7)
Uterine aspiration§	13 (8.8)	35 (23.5)	0.37 (0.21–0.68)

^*Relative risks were adjusted for trial site with use of the Mantel–Haenszel method.

^†Treatment success was defined as gestational sac expulsion with one misoprostol dose by the first follow-up visit and no additional intervention within 30 days after treatment.

^‡The rate of treatment success by the first follow-up visit was significantly higher in the mifepristone-pretreatment group than in misoprostol-alone group (P<0.001).

^§Indications for uterine aspiration included participant request and clinical recommendation.