Table 3.
Top 13 regulated metabolites in serum among dams in the hsFLT1/rtTA mouse model.
| Fold change | log2(FC) | p–value | -log10(p) | |
|---|---|---|---|---|
| PC ae C40:3 | 0.27987 | −1.8372 | 0.001 | 3.1843 |
| PC ae C38:3 | 0.45671 | −1.1306 | 0.002 | 2.7442 |
| lysoPC a C18:1 | 0.449 | −1.1552 | 0.004 | 2.4119 |
| PC ae C38:1 | 0.36779 | −1.443 | 0.005 | 2.2804 |
| Gly | 0.35951 | −1.4759 | 0.009 | 2.0239 |
| PC ae C42:4 | 0.32027 | −1.6427 | 0.010 | 2.0139 |
| PC aa C42:4 | 0.3671 | −1.4458 | 0.012 | 1.909 |
| Sarcosine | 0.44167 | −1.1789 | 0.019 | 1.7266 |
| lysoPC a C20:3 | 0.31089 | −1.6855 | 0.024 | 1.6226 |
| PC aa C40:3 | 0.40968 | −1.2874 | 0.041 | 1.3855 |
| Kynurenine | 2.1765 | 1.122 | 0.010 | 2.0002 |
| t4-OH-Pro | 2.0757 | 1.0536 | 0.013 | 1.9025 |
| Histamine | 2.0072 | 1.0052 | 0.021 | 1.6826 |
aa, diacyl; ae, acyl-alkyl; FC, fold change; Gly, glycine; lysoPC, lyso phosphatidylcholine; p, probability; PC, phosphatidylcholine; t4-OH-Pro; trans-4-Hydroxyproline.