Skip to main content
. 2019 Mar 28;19:277. doi: 10.1186/s12885-019-5447-1

Fig. 5.

Fig. 5

Stable HPV16 integration in the tumor cell genome with chromosome deletion. Mapping of the two viral/cell junctions in a co-linear (2J-COL) pattern is shown. The coordinates of the human (junction to chromosome, hg38 reference) and viral (junction to junction) are indicated, as well as the chromosomal locus of insertion. HPV16 insertion is associated with the deletion of 178,808 bp in the cell genome, including FAM241A and four pseudogenes