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. 2019 Mar 28;12:68. doi: 10.1186/s13068-019-1415-x

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Effects of menA gene deletion on the biosynthesis of DMK, MK and squalene. a HPLC chromatogram of DMK and MK extracted from JM109 (DE3) [Δpgi] and JM109 (DE3) [Δpgi, ΔmenA]. b Squalene production in ECHSQ5 and ECHSQ6. Data represent the mean ± SD of duplicate samples in three separate experiments