Table 3.
Characteristics of included studies
| Author | Year/country | Study design | LCC | RCC | LCC | RCC | ||
|---|---|---|---|---|---|---|---|---|
| wt | mut | wt | mut | HR(95%CI) | HR(95%CI) | |||
| Chiu JW | 2018/Canada | P | 65 | 46 | 36 | 37 | – | – |
| Hou Y | 2018/China | R | 196 | 117 | 62 | 86 | – | – |
| Natsume S | 2018/Japan | R | 327 | 97 | 98 | 53 | 0.58 (0.37–0.86) | – |
| Charlton ME | 2017/USA | R | 2849 | 2701 | 1.18 (1.05–1.3) | 0.93 (0.83–1.03) | ||
| Gao XH | 2017/China | P | 42 | 30 | 27 | 16 | – | – |
| Kim ST | 2017/Korea | R | 115 | 9 | 25 | 4 | – | – |
| Chang YY | 2016/China | P | 425 | 221 | 221 | 187 | – | – |
| Sasaki K | 2016/USA | R | 201 | 96 | 65 | 64 | 1.81 (1.11–2.96) | 1.03 (0.51–2.08) |
| Sun P | 2016/China | R | 60 | 48 | 44 | 40 | – | – |
| Kodaz H | 2015/Turkey | R | 80 | 72 | 13 | 12 | – | – |
| Ye JX | 2015/China | R | 100 | 50 | 94 | 67 | – | – |
| Tong JH | 2014/China | R | 680 | 461 | 156 | 209 | – | – |
| von Einem JC | 2014/Germany | P | 68 | 32 | 27 | 19 | 1.3 (0.68–2.34) | 0.63 (0.43–0.92) |
| Cushman- Vokoun AM | 2013/USA | R | 13 | 16 | 21 | 15 | – | – |
| Zhu XL | 2012/China | R | 79 | 45 | 59 | 47 | – | – |
| Abubaker J | 2009/Saudi Arabia | R | 79 | 62 | 26 | 18 | – | – |
| Bleeker WA | 2000/Netherlands | R | 26 | 3 | 16 | 10 | – | – |
LCC left-side colon cancer, RCC right-side colon cancer, wt KRAS wild type, mut KRAS mutant type, HR hazard ratio, CI confidence interval, P prospective, R retrospective