Fig. 3.

Results of the investigated genes in lung tissue by quantitative real-time polymerase chain reaction. The plot shows the percentage differences in cytokine copy numbers versus Sus scrofa peptidylprolyl isomerase A (PPIA) between the control group (constant PO₂) and the intervention group (cyclic PO₂). TNF-α, Sus scrofa tumor necrosis factor; IL-1β, Sus scrofa interleukin 1 beta; IL-6, Sus scrofa interleukin 6; iNOS, Sus scrofa nitric oxide synthase 2; PGH2, Sus scrofa prostaglandin G/H synthase-2. Statistical significance was carried out by the Wilcoxon signed-rank test: NS ≥ 0.05; 0.01 ≤ * < 0.05; 0.001 ≤ ** < 0.01; 0.001 ≤ *** < 0.0001. Box plots represent the median, 25% and 75% percentile, whiskers the minimum and maximum values