Table 1.
Summary of individual studies of chronic periodontitis
| GEO gene set ID | GSE10334 | GSE16134 | GSE23586 |
|---|---|---|---|
| Platform | GPL570: Affymetric Human Geneme U133 plus 2.0 Array | ||
| Number of Healthy Control Persons vs. Chronic Periodontitis Persons | 64 vs. 63 | 69 vs. 65 | 3 vs. 3 |
| Clinical Data | |||
| Healthy Control | PD ≤ 4 mm, AL ≤ 2 mm, BoP- | PD ≤ 4 mm, AL ≤ 2 mm, BoP- | PD ≤ 2 mm, AL = 0, BoP-, GI = 0 |
| Chronic Periodontitis | PD > 4 mm, AL ≥ 3 mm, BoP+ | PD > 4 mm, AL ≥ 3 mm, BoP+ | PD ≥ 5 mm, AL ≥ 5 mm, BoP+, GI ≥ 1 |
| Diabetes | Not | Not | Not |
| Pregnant | Not | Not | Not |
| Smoking | Not | Not | Not |
| No systemic antibiotics or anti-inflammatory drugs for ≥6 months | No systemic antibiotics or anti-inflammatory drugs for ≥6 months | No systemic antibiotics or anti-inflammatory drugs for ≥6 months | |
| PubMed ID | 18,980,520 | 19,835,625 | 21,382,035 |
| 24,646,639 | |||
PD Probing Depth, AL Attachment Level, BoP Bleeding on Probing, GI Gingival Index