Table 3.
Common downregulated DEGs (p < 0.05, FC < −2) in chronic periodontitis
| Gene Symbol | Gene Description | Probe |
|---|---|---|
| AADAC | arylacetamide deacetylase | 205969_at |
| AADACL2 | arylacetamide deacetylase like 2 | 240420_at |
| ABCA12 | ATP binding cassette subfamily A member 12 | 215465_at |
| AHNAK2 | AHNAK nucleoprotein 2 | 1558378_a_at |
| ARG1 | arginase 1 | 206177_s_at |
| ATP6V1C2 | ATPase H+ transporting V1 subunit C2 | 1552532_a_at |
| BPIFC | BPI fold containing family C | 1555773_at |
| CALML5 | calmodulin like 5 | 220414_at |
| CLDN20 | claudin 20 | 1554812_at |
| CWH43 | cell wall biogenesis 43 C-terminal homolog | 220724_at |
| CYP2C18 | cytochrome P450 family 2 subfamily C member 18 | 215103_at |
| CYP3A5 | cytochrome P450 family 3 subfamily A member 5 | 205765_at |
| DSC1 | desmocollin 1 | 207324_s_at |
| DSC2 | desmocollin 2 | 204750_s_at |
| ELOVL4 | ELOVL fatty acid elongase 4 | 219532_at |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B | 220161_s_at |
| EXPH5 | exophilin 5 | 213929_at, 214734_at |
| FLG | filaggrin | 215704_at |
| FLG2 | filaggrin family member 2 | 1569410_at |
| FOXN1 | forkhead box N1 | 1558687_a_at |
| FOXP2 | forkhead box P2 | 1555647_a_at, 235201_at, 1555516_at |
| GJA3 | gap junction protein alpha 3 | 239572_at |
| KRT10 | keratin 10 | 207023_x_at |
| LGALSL | galectin like | 226188_at |
| LOR | loricrin | 207720_at |
| LY6G6C | lymphocyte antigen 6 family member G6C | 207114_at |
| MAP 2 | microtubule associated protein 2 | 225540_at |
| MUC15 | mucin 15, cell surface associated | 227241_at, 227238_at |
| NEFL | neurofilament light | 221916_at, 221805_at |
| NEFM | neurofilament medium | 205113_at |
| NOS1 | nitric oxide synthase 1 | 239132_at |
| NPR3 | natriuretic peptide receptor 3 | 219789_at |
| NSG1 | neuronal vesicle trafficking associated 1 | 209570_s_at |
| POF1B | POF1B actin binding protein | 219756_s_at, 1555383_a_at |
| PTGER3 | prostaglandin E receptor 3 | 213933_at |
| RORA | RAR related orphan receptor A | 210426_x_at, 210479_s_at, 235567_at, 226682_at |
| RPTN | repetin | 1553454_at |
| SH3GL3 | SH3 domain containing GRB2 like 3, endophilin A3 | 205637_s_at |
| SLC16A9 | solute carrier family 16 member 9 | 227506_at |
| SPAG17 | sperm associated antigen 17 | 233516_s_at |
| WASL | Wiskott-Aldrich syndrome like | 205809_s_at |
| YOD1 | YOD1 deubiquitinase | 227309_at |