Table 1. Baseline characteristics of healthy controls, hypertensive patients, and stroke patients.
| Healthy controls | Hypertensive patients | Stroke patients | F/χ2 | p | |
|---|---|---|---|---|---|
| Age (y) | 64.35 ± 9.22 | 66.19 ± 9.84 | 65.77 ± 9.32 | 2.28 | 0.103 |
| Gender (M/F) | 138/80 | 143/100 | 78/54 | 1.10 | 0.576 |
| Hcy (μmol/L) | 14.57 ± 5.70 | 16.97 ± 12.89 | 21.13 ± 18.56 | 11.31 | <0.001 |
| UA (μmol/L) | 365.89 ± 97.06 | 364.50 ± 97.67 | 365.91 ± 87.25 | 0.02 | 0.985 |
| TG (mmol/L) | 1.75 ± 1.47 | 1.92 ± 1.63 | 1.79 ± 0.91 | 0.92 | 0.401 |
| TC (mmol/L) | 5.12 ± 1.02 | 5.11 ± 1.03 | 4.91 ± 1.07 | 2.00 | 0.137 |
| BMI (kg/m2) | 23.46 ± 3.08 | 24.44 ± 2.93* | 24.49 ± 2.78* | 7.82 | 0.001 |
| Glu (mmol/L) | 4.96 ± 0.81 | 5.67 ± 1.34* | 5.64 ± 1.07* | 27.33 | <0.001 |
| WC (cm) | 84.69 ± 9.80 | 87.03 ± 9.00* | 87.11 ± 10.38* | 4.18 | 0.016 |
| HC (cm) | 93.62 ± 9.54 | 95.69 ± 7.99* | 95.15 ± 9.63 | 3.22 | 0.041 |
| SBP (mmHg) | 123.57 ± 13.81 | 134.43 ± 16.47* | 135.69 ± 15.86* | 37.40 | <0.001 |
| DBP (mmHg) | 77.95 ± 8.43 | 82.59 ± 11.18* | 82.76 ± 11.27* | 14.41 | <0.001 |
| Smoking (no/yes) | 182/36 | 214/29 | 115/17 | 2.15 | 0.341 |
| Drinking (no/yes) | 136/82 | 176/67 | 112/20 | 20.53 | <0.001 |
| Antihypertensive drugs (no/yes) | – | 50/193 | 13/119# | 7.04 | 0.008 |
| PMR-CBS (%) | 30.53 ± 26.91 | 50.61 ± 25.73* | 38.05 ± 24.66* # | 34.93 | <0.001 |
Hcy: plasma homocysteine, UA: uric acid, TG: triglycerides, TC: total cholesterol, BMI: body mass index, Glu: blood glucose, WC: waist circumference, HC: hip circumference, SBP: systolic blood pressure, DBP: diastolic blood pressure, PMR: percent of methylated reference.
*
p<0.05, compared with healthy controls.
#
p<0.05, compared with hypertensive patients.