Table 3. Number of occurrences of different ring-types in the first 1000 structures of the ZINC data set (“ZINC”), and in the 1000 structures generated by the GB-GM method using the ZINC probabilities (“GB-GM (62%)”) and a probability set where the probability of [*] [*]–[*] type bonding is increased to 80% (“GB-GM (80%)”).

Ring-type	ZINC	GM (62%)	GM (80%)
[*]1–[*]–[*]1	57	104	57
[*]1–[*]–[*]–[*]1	17	33	10
[*]1–[*]–[*]–[*]–[*]1	280	15	4
[*]1 [*]–[*]–[*]–[*]1	120	396	408
[*]1 [*]–[*] [*]–[*]1	470	132	221
[*]1–[*]–[*]–[*]–[*]–[*]1	409	64	2
[*]1 [*]–[*]–[*]–[*]–[*]1	77	363	104
[*]1 [*]–[*] [*]–[*]–[*]1	100	591	405
[*]1 [*]–[*]–[*] [*]–[*]1	7	321	202
[*]1 [*]–[*] [*]–[*] [*]1	1206	479	850
7-Membered ring	24	0	0
8-Membered ring	1	0	0
Total	2768	2498	2263