Fig. 4:

Synchronized L1 worms were pre-treated for 30 min with 5 μM VU0063088 or VU0026921 and then exposed to 25 or 50 mM MnCl₂ for 1 h, followed by plating 30–60 worms in NGM and scoring lethality. Results are expressed as the percentage of animals alive 48 h post-treatment relative to day 0 and are expressed as mean ± S.E.M. of 3 experiments. * p <0.05, ** p <0.01, *** p <0.001 compared to vehicle (VEH) control group. Two-way ANOVA followed by post hoc Dunnet’s test.