Figure 2.

Glycolysis and tricarboxylic acid (TCA) cycle plasma intermediates are affected by cancer and chemotherapy. Representative diagram of glycolysis and TCA cycle showing the metabolites concentration (expressed in mM) detected in the plasma of vehicle‐treated animals (V), C26 hosts (CC), Folfiri‐treated mice (F), or Folfiri‐treated tumour bearers (CCF). Data are expressed as means ± standard deviation. Statistical significance was evaluated by two‐way analysis of variance, and significant differences (at least P < 0.05) were reported as ^a P vs. V; ^b P vs. CC; ^c P vs. F.