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. 2019 Jan 24;10(1):140–154. doi: 10.1002/jcsm.12360

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© 2019 The Authors. Journal of Cachexia, Sarcopenia and Muscle published by John Wiley & Sons Ltd on behalf of the Society on Sarcopenia, Cachexia and Wasting Disorders

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Muscle metabolites involved in amino acid and fatty acid metabolism. Leucine (Leu), isoleucine (Iie), and valine (Val) levels (expressed in mM) in the skeletal muscle of vehicle‐treated animals (V), C26 hosts (CC), Folfiri‐treated mice (F), or Folfiri‐treated tumour bearers (CCF) (A). Free carnitine (C0), acetylcarnitine (C2), acylcarnitine (C3), octanoylcarnitine (C8), decanoylcarnitine (10), and palmitoylcarnitine (16) levels (expressed in mM) in the muscle of vehicle‐treated animals (V), C26 hosts (CC), Folfiri‐treated mice (F), or Folfiri‐treated tumour bearers (CCF) (B). Data are expressed as means ± standard deviation. Statistical significance was evaluated by two‐way analysis of variance, and significant differences (at least P < 0.05) were reported as ^a P vs. V; ^b P vs. CC; ^c P vs. F.