Table 1.
Clinicopathologic findings in 64 cases of hibernoma mimicking atypical lipomatous tumor.
| Case no. | Age | Sex | Tumor site (side) | Tumor size (cm) | Margin status |
MDM2 IHC |
MDM2 FISH |
CDK4 IHC |
Follow up (months) |
|---|---|---|---|---|---|---|---|---|---|
| 1 | 78 | F | Inguinal region (R) | 6 | - | Negative | - | Negative | - |
| 2 | 53 | M | Thigh | 10 | - | Negative | - | Negative | - |
| 3 | 37 | M | Thigh (L) | 18 | - | - | - | - | - |
| 4 | 37 | M | Thigh (L) | 18 | Negative | - | - | - | - |
| 5 | 74 | M | Thigh (L) | 23 | - | - | - | - | - |
| 6 | 49 | M | Thigh (R) | 14 | - | - | - | - | - |
| 7 | 43 | F | Thigh (L) | 15 | Positive | - | - | - | ANED (84) |
| 8 | 56 | M | Thigh (L) | 19 | - | - | - | - | - |
| 9 | 50 | M | Inguinal region (L) | 3.5 | Negative | Negative | - | Negative | ANED (165) |
| 10 | 57 | F | Thigh (L) | 12.5 | - | - | - | - | ANED (135) |
| 11 | 42 | M | Thigh (R) | 10 | Negative | Negative | - | Negative | ANED (76) |
| 12 | 39 | M | Thigh (L) | 8.7 | Negative | - | - | - | - |
| 13 | 25 | F | Axilla (L) | 11 | Negative | - | - | - | ANED (150) |
| 14 | 39 | M | Thigh (R) | 20.5 | Positive | - | - | - | ANED (118) |
| 15 | 40 | F | Thigh (R) | 17 | - | - | - | - | - |
| 16 | 61 | F | Thigh (L) | 15 | - | Negative | - | Negative | - |
| 17 | 42 | F | Thigh (L) | 20 | - | - | - | - | - |
| 18 | 49 | M | Thigh (L) | 13 | Negative | Negative | - | Negative | - |
| 19 | 33 | F | Thigh (R) | 11 | Negative | Negative | - | Negative | - |
| 20 | 40 | M | Thigh (R) | 14.7 | - | - | - | - | - |
| 21 | 38 | M | Popliteal fossa (L) | 6 | - | - | - | - | - |
| 22 | 39 | F | Thigh (R) | 14 | Positive | Negative | - | Negative | - |
| 23 | 44 | F | Lower back | 4 | - | Negative | - | Negative | - |
| 24 | 28 | M | Thigh (L) | 14.2 | Negative | - | - | - | - |
| 25 | 42 | M | Thigh (L) | 18.5 | - | - | - | - | - |
| 26 | 24 | M | Thigh (R) | 8 | - | - | - | - | ANED (48) |
| 27 | 65 | M | Foot (R) | 7 | - | Negative | - | Negative | - |
| 28 | 28 | F | Groin (R) | 11 | Negative | - | - | - | - |
| 29 | 59 | M | Thigh (R) | 6.2 | - | Negative | - | Negative | - |
| 30 | 66 | F | Thigh (L) | 6 | Positive | Negative | - | Negative | - |
| 31 | 50 | F | Thigh (R) | 18 | Positive | Negative | - | Negative | - |
| 32 | 56 | F | Thigh (L) | 12.7 | Negative | - | - | - | - |
| 33 | 39 | F | Thigh (L) | 14 | Positive | Negative | - | Negative | - |
| 34 | 43 | F | Thigh (L) | 8.1 | Positive | Negative | - | Negative | - |
| 35 | 52 | M | Thigh (R) | 10 | Negative | Negative | - | Negative | - |
| 36 | 78 | F | Inguinal region (L) | 8 | Negative | - | - | - | ANED (40) |
| 37 | 39 | M | Buttock (R) | 17.3 | Negative | Negative | - | Negative | - |
| 38 | 58 | F | Thigh (L) | 13.5 | - | Negative | - | Negative | - |
| 39 | 50 | F | Buttock (R) | 15.5 | - | Negative | - | Negative | ANED (1) |
| 40 | 40 | M | Thigh (L) | 15 | Negative | Negative | - | Negative | ANED (45) |
| 41 | 38 | M | Thigh (L) | 11 | - | Negative | - | Negative | - |
| 42 | 61 | M | Abdominal wall (R) | 14 | - | - | - | - | - |
| 43 | 43 | F | Leg (L) | 7 | - | - | - | - | - |
| 44 | 46 | F | Thigh (L) | 7.7 | - | - | - | - | - |
| 45 | 46 | F | Thigh (R) | 20 | - | Negative | - | Negative | ANED (9) |
| 46 | 26 | M | Buttock (R) | 14 | Positive | - | Negative | - | - |
| 47 | 47 | M | Buttock/lower back | 15 | - | Negative | - | Negative | - |
| 48 | 31 | F | Thigh (L) | 14 | Positive | Negative | - | Negative | - |
| 49 | 68 | F | Thigh (L) | 10 | - | Negative | - | Negative | - |
| 50 | 31 | M | Thigh (R) | 14 | - | Negative | - | Negative | - |
| 51 | 44 | M | Thigh (L) | 7.3 | Positive | - | Negative | - | ANED (23) |
| 52 | 43 | F | Thigh (R) | 10 | - | Negative | - | Negative | - |
| 53 | 34 | F | Thigh (L) | 9.5 | - | Negative | - | Negative | - |
| 54 | 47 | M | Thigh (L) | 12 | Negative | Negative | - | Negative | - |
| 55 | 45 | F | Groin (L) | 11 | Positive | Negative | - | Negative | - |
| 56 | 51 | M | Buttock (R) | 14 | - | Negative | - | Negative | - |
| 57 | 48 | M | Buttock (R) | 15.8 | - | - | - | - | ANED (7) |
| 58 | 30 | F | Buttock (R) | 14.5 | Negative | - | - | - | ANED (2.5) |
| 59 | 45 | M | Thigh (L) | 3.8 | - | Negative | - | Negative | - |
| 60 | 28 | M | Thigh (L) | 6.7 | - | Negative | - | Negative | - |
| 61 | 36 | F | Inguinal region | 23 | - | - | Negative | - | - |
| 62 | 69 | M | Buttock (L) | 23 | - | - | Negative | Negative | - |
| 63 | 41 | M | Abdominal wall (L) | 8.4 | Positive | - | Negative | - | ANED (1) |
| 64 | 38 | F | Stomach | 10 | Negative | - | Negative | - | ANED (5) |
ANED: alive, no evidence of disease; IHC: immunohistochemistry; L: left; R: right