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. 2018 Oct 30;10(1):54–62. doi: 10.1002/jcsm.12335

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© 2018 The Authors. Journal of Cachexia, Sarcopenia and Muscle published by John Wiley & Sons Ltd on behalf of the Society on Sarcopenia, Cachexia and Wasting Disorders

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Transcriptional consequences. Transcript levels of (A) nppa, (B) nppb, (C) col3a1, (D) col5a1, (E) murf‐1, and (F) atrogin‐1 in the hearts from sham‐operated control animals and 60 min middle cerebral artery occlusion (MCAO) animals as indicated, normalized to control (n = 5–6/group) at time points 1, 3, and 14 days after 60 min MCAO and sham operation. (G) Tissue noradrenaline concentration in the hearts of sham‐operated and 60 min MCAO mice, respectively (n = 6/group). (H) Transcript levels of tyrosinhydroxylase (th) in cardiac ganglia from sham‐operated and MCAO‐operated animals, 3 days after intervention (n = 6–7/group). All results are shown as mean ± standard deviation. ^* P < 0.05 sham vs. MCAO. (I) Working model.