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. 2019 Mar 18;54(5):1511–1524. doi: 10.3892/ijo.2019.4751

Figure 2.

Figure 2

ncRNAs related to drug resistance in gastric cancer. Many ncRNAs are related to drug resistance in gastric cancer by modulating the sensitivity of gastric cancer cells to drugs, and the molecular mechanisms contribute to a complex regulatory network. Drug resistance related to other miRNAs (oxaliplatin resistance, paclitaxel resistance, trastuzumab resistance, lapatinib resistance, epirubicin resistance, oxaliplatin resistance, capecitabine resistance), drug resistance related to lncRNAs (cisplatin resistance, adriamycin resistance, oxaliplatin resistance, 5-fluorouracil resistance, paclitaxel resistance, vincristine resistance). The arrows represent an inducing effect and the T symbols indicate a reversing effect. ncRNAs, non-coding RNAs; ADR/DOX, adriamycin/doxorubicin; 5-FU, 5-fluorouracil; MDR, multi-drug resistance; VCR, vincristine; DDP, cisplatin.