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. 2019 Feb 27;54(5):1676–1690. doi: 10.3892/ijo.2019.4726

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Copyright: © Hong et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Based on the data of the Transwell assay, silencing LOXL2 may suppress renal cell carcinoma cell invasion. (A) The number of 786-O cells invading the basolateral chamber was significantly reduced. (B) Quantified number of invaded cells. ^*P<0.05 vs. the blank and si-NC groups. (C) The number of Caki1 cells invading the basolateral chamber was significantly increased. (D) Quantified number of invaded cells. ^*P<0.05 vs. the blank and empty vector groups; ^#P<0.05 vs. the LOXL2 vector group. One-way analysis of variance was used for comparison and the experiment was repeated three times. LOXL2, lysyl oxidase-like 2; NC, negative control; si-, small interfering RNA.