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. 2019 Mar 19;54(5):1567–1578. doi: 10.3892/ijo.2019.4756

Figure 7.

Figure 7

miR-8485 inhibitor suppresses the migration and invasion of DOK and SCC15 cells. (A) miR-8485 expression was detected by reverse transcription-quantitative polymerase chain reaction after miR-8485 inhibitor was transfected into the DOK cells. (B) miR-8485 expression was detected by reverse transcription-quantitative polymerase chain reaction after miR-8485 inhibitor was transfected into the SCC15 cells. (C) The effect of the miR-8485 inhibitor on proliferation was analyzed by the cell confluence of DOK cells. (D) The effect of the miR-8485 inhibitor on proliferation was analyzed by the cell confluence of SCC15 cells. (E) The wound healing assay revealed that compared with the NC-inhibitor, the miR-8485 inhibitor suppressed the migration of the DOK cells. Representative images with a magnification of ×10 are depicted. (F) The wound healing assay revealed that compared with the NC-inhibitor, the miR-8485 inhibitor suppressed the migration of the SCC15 cells. Representative images with a magnification of ×10 are depicted. (G) The Matrigel invasion assay indicated that compared with the NC-inhibitor, the miR-8485 inhibitor suppressed the invasion ability of the DOK cells. Representative images with a magnification of ×20 are depicted. (H) The Matrigel invasion assay indicated that compared with the NC-inhibitor, the miR-8485 inhibitor suppressed the invasion ability of the SCC15 cells. Representative images with a magnification of ×20 are depicted. *P<0.05 and **P<0.01, compared with NC groups. NC, negative control; miR, microRNA.