Table 4. RRs of second primary cancers after seminoma and non-seminoma.
Second cancer site | Seminoma | Non-seminoma | ||||
---|---|---|---|---|---|---|
Cases | RR1 | 95%CI2 | Cases | RR | 95%CI | |
All (excluding testis) | 445 | 1.28 | 1.16–1.40 | 183 | 1.43 | 1.24–1.66 |
Upper aerodigestive tract | 8 | 0.75 | 0.37–1.50 | 4 | 0.89 | 0.34–2.38 |
Esophagus | 9 | 2.17 | 1.13–4.18 | 0 | -- | -- |
Stomach | 14 | 1.67 | 0.99–2.82 | 2 | 0.72 | 0.18–2.88 |
Colorectum | 46 | 1.26 | 0.94–1.68 | 21 | 1.64 | 1.07–2.51 |
Liver | 9 | 1.30 | 0.67–2.49 | 3 | 1.22 | 0.39–3.78 |
Pancreas | 12 | 1.64 | 0.93–2.89 | 2 | 0.79 | 0.20–3.16 |
Lung | 21 | 0.79 | 0.51–1.21 | 15 | 1.62 | 0.98–2.69 |
Prostate | 115 | 1.11 | 0.92–1.33 | 38 | 1.22 | 0.88–1.67 |
Testis | 123 | 23.30 | 19.49–27.86 | 66 | 11.61 | 9.11–14.80 |
Kidney | 23 | 2.22 | 1.48–3.34 | 9 | 2.20 | 1.15–4.23 |
Urinary bladder | 34 | 1.57 | 1.12–2.19 | 19 | 2.57 | 1.64–4.03 |
Melanoma | 22 | 1.15 | 0.76–1.74 | 9 | 1.10 | 0.61–1.98 |
Skin, squamous cell | 21 | 1.35 | 0.88–2.08 | 11 | 1.87 | 0.97–3.59 |
Eye | 3 | 2.87 | 0.92–8.90 | 0 | -- | -- |
Nervous system | 17 | 1.53 | 0.95–2.46 | 7 | 1.12 | 0.53–2.34 |
Thyroid gland | 6 | 3.19 | 1.43–7.10 | 2 | 1.75 | 0.44–7.01 |
Endocrine glands | 7 | 1.48 | 0.70–3.10 | 0 | -- | -- |
Connective tissue | 6 | 2.39 | 1.07–5.32 | 4 | 3.08 | 1.16–8.23 |
Non-Hodgkin lymphoma | 26 | 1.96 | 1.33–2.88 | 10 | 1.73 | 0.93–3.21 |
Myeloma | 5 | 1.05 | 0.44–2.51 | 4 | 2.36 | 0.89–6.29 |
Leukemia | 21 | 1.96 | 1.28–3.00 | 10 | 2.16 | 1.16–4.02 |
Acute myeloid leukemia | 8 | 4.27 | 2.13–8.55 | 2 | 2.42 | 0.60–9.68 |
Chronic myeloid leukemia | 2 | 2.01 | 0.50–8.06 | 3 | 5.01 | 1.61–15.56 |
Acute lymphoid leukemia | 2 | 4.42 | 1.10–17.71 | 1 | 2.73 | 0.38–19.38 |
Chronic lymphoid leukemia | 6 | 1.55 | 0.69–3.45 | 1 | 0.75 | 0.10–5.29 |
Others | 3 | 1.14 | 0.37–3.53 | 3 | 2.62 | 0.84–8.12 |
CUP3 | 12 | 1.44 | 0.82–2.53 | 6 | 1.99 | 0.89–4.43 |
RR1 = relative risk, 95%CI2 = 95% confidence interval, bold font indicates that the lower limit of 95%CI does not include 1.00. CUP3 = cancer of unknown primary.