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Effect of different concentrations of Sfrp5 on markers of proliferation: (A) Cyclin-B1 (N = 5), (B) Ki67 (N = 5) and (C) proliferating-cell-nuclear-antigen (PCNA) (N = 5) in INS-1E cells. Data were normalised to eukaryotic initiation factor 4A-II (EIF4A2). Staurosporine was used as positive control for inhibition of cell proliferation. Data are presented as mean + SEM (fold change relative to control). $, p = 0.056; *, p<0.05; **, p<0.01 vs. control.
