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. 2019 Mar 18;13(3):e0007243. doi: 10.1371/journal.pntd.0007243

Table 1. Characteristics of matched cases and controls including demographic characteristics, risk factors, underlying illnesses, and mortality.

Melioidosis Cases
(no. = 242) (%§)
Melioidosis Controls
(no. = 242) (%§)
p-value x2
Mean Age
    Male 47.75 (16.6) 47.82 (16.4)
    Female 42.95 (18.6) 42.93 (18.7)
Male 185 (76.4) 185 (76.4)
    Malay 170 (70.2) 170 (70.2)
    Chinese 9 (3.7) 9 (3.7)
    Indian 3 (1.2) 3 (1.2)
    Others 3 (1.2) 3 (1.2)
Female 57 (23.6) 57 (23.6)
    Malay 55 (22.7) 55 (22.7)
    Chinese 0 0
    Indian 1 (0.4) 1 (0.4)
    Others 1 (0.4) 1 (0.4)
Occupation
    Low** 26 (10.7) 54 (22.3) <0.001 11.74
    Medium 69 (28.5) 75 (31.0) 0.60 0.36
    High* 41 (16.9) 25 (10.3) 0.04 4.49
    Unknown 106 (43.8) 88 (36.4) 0.12 2.79
Smoker
    Yes 52 (21.5) 46 (19.0) 0.678 0.17
    No 109 (45.0) 87 (36.0)
    Unknown 81 (33.5) 109 (45.0)
Alcohol Consumption
    Yes 3 (1.2) 2 (0.8) 0.202 0.65
    No 239 (98.8) 240 (99.2)
Underlying Illnesses
    Diabetes Mellitus** 145 (59.9) 73 (30.2) <0.001 43.27
    Chronic Renal Failure** 19 (7.9) 5 (2.1) 0.003 8.59
    Chronic Lung Disease 3 (1.2) 1 (0.3) 0.315 1.01
    HIV/AIDs 4 (1.7) 1 (0.3) 0.177 1.82
    Immunocompromised States 4 (1.7) 0
    Other Diseases 87 (36.0) 79 (32.7) 0.045 4.03

Data shown as no. (%); p-value <0.05 * and <0.01 **

data shown as mean (standard deviation)

§ percentages calculated based on total subjects (no.) for each disease group.

A few of the conditions included in the “Other Diseases” category are hypertension, hypercholesterolaemia, heart disease, hepatitis B and C, thalassemia, and tuberculosis. A majority of the deceased patients presented with various combinations of the underlying illnesses, most commonly, diabetes mellitus and chronic renal failure, as well as, diabetes mellitus and other diseases.