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. 2019 Mar 18;13(3):e0007243. doi: 10.1371/journal.pntd.0007243

Table 3. Case-fatality ratio and relative risk of death by socio-demographic and clinical factors among melioidosis culture-confirmed and suspected cases.

Melioidosis Confirmed Cases (n = 220) Melioidosis Suspected Cases (n = 193)
n§ Deaths RR 95% CI n§ Deaths RR 95% CI
Case Fatality Ratio 220 92 41.8 35.5–48.4 193 38 19.7 14.7–25.9
Sex
    Male 163 68 Ref. 124 25 Ref.
    Female 57 24 1.01 0.71–1.44 69 13 0.93 0.51–1.71
Age
    0–24 34 9 0.53 0.29–0.97* 26 2 0.32 0.08–1.26
    25–54 118 49 0.83 0.60–1.14 85 16 0.77 0.43–1.38
    55+ 68 34 Ref. 82 20 Ref.
Race
    Malay 199 85 Ref. 175 33 Ref.
    Chinese 9 3 0.78 0.31–1.99 11 3 1.45 0.53–3.98
    Indian 7 3 1.00 0.42–2.40 3 0 0.00 NA
    Others 5 1 0.47 0.08–2.72 4 2 2.65 0.95–7.41
Occupation
    Low 24 6 Ref. 32 5 Ref.
    Medium 68 19 1.12 0.51–2.47 72 12 1.07 0.41–2.78
    High 34 12 1.41 0.62–3.23 28 5 1.14 0.37–3.54
    Unknown 94 55 2.34 1.15–4.78* 61 16 1.68 0.68–4.16
Smoker
    Yes 41 16 1.13 0.71–1.79 40 11 1.56 0.82–2.99
    No 107 37 Ref. 108 19 Ref.
    Unknown 72 39 1.57 1.12–2.19* 45 8 1.01 0.48–2.14
Underlying Illnesses
    Diabetes Mellitus 128 61 1.41 1.01–1.99* 88 23 1.83 1.02–3.29*
    Chronic Renal Failure 18 10 1.37 0.88–2.14 10 5 2.77 1.39–5.54*
    Chronic Lung Disease 3 2 1.61 0.71–3.63 3 0 0 NA
    HIV/AIDs 3 1 0.79 0.16–3.97 3 1 1.71 0.34–8.70
    Immunocompromised States 5 2 0.96 0.32–2.83 2 0 0 NA
    Other Diseases 83 30 0.80 0.57–1.12 58 14 1.36 0.76–2.43

§ Individuals who were transferred to a different hospital or discharged from the hospital at their own risk were excluded from the analysis as we do not know if they final clinical outcome was death

data shown as case-fatality ratio rather than relative risk ratio

* indicates a p-value <0.05.