Table 3. Case-fatality ratio and relative risk of death by socio-demographic and clinical factors among melioidosis culture-confirmed and suspected cases.
Melioidosis Confirmed Cases (n = 220) | Melioidosis Suspected Cases (n = 193) | |||||||
---|---|---|---|---|---|---|---|---|
n§ | Deaths | RR | 95% CI | n§ | Deaths | RR | 95% CI | |
Case Fatality Ratio‡ | 220 | 92 | 41.8 | 35.5–48.4 | 193 | 38 | 19.7 | 14.7–25.9 |
Sex | ||||||||
Male | 163 | 68 | Ref. | — | 124 | 25 | Ref. | — |
Female | 57 | 24 | 1.01 | 0.71–1.44 | 69 | 13 | 0.93 | 0.51–1.71 |
Age | ||||||||
0–24 | 34 | 9 | 0.53 | 0.29–0.97* | 26 | 2 | 0.32 | 0.08–1.26 |
25–54 | 118 | 49 | 0.83 | 0.60–1.14 | 85 | 16 | 0.77 | 0.43–1.38 |
55+ | 68 | 34 | Ref. | — | 82 | 20 | Ref. | — |
Race | ||||||||
Malay | 199 | 85 | Ref. | — | 175 | 33 | Ref. | — |
Chinese | 9 | 3 | 0.78 | 0.31–1.99 | 11 | 3 | 1.45 | 0.53–3.98 |
Indian | 7 | 3 | 1.00 | 0.42–2.40 | 3 | 0 | 0.00 | NA |
Others | 5 | 1 | 0.47 | 0.08–2.72 | 4 | 2 | 2.65 | 0.95–7.41 |
Occupation | ||||||||
Low | 24 | 6 | Ref. | — | 32 | 5 | Ref. | — |
Medium | 68 | 19 | 1.12 | 0.51–2.47 | 72 | 12 | 1.07 | 0.41–2.78 |
High | 34 | 12 | 1.41 | 0.62–3.23 | 28 | 5 | 1.14 | 0.37–3.54 |
Unknown | 94 | 55 | 2.34 | 1.15–4.78* | 61 | 16 | 1.68 | 0.68–4.16 |
Smoker | ||||||||
Yes | 41 | 16 | 1.13 | 0.71–1.79 | 40 | 11 | 1.56 | 0.82–2.99 |
No | 107 | 37 | Ref. | — | 108 | 19 | Ref. | — |
Unknown | 72 | 39 | 1.57 | 1.12–2.19* | 45 | 8 | 1.01 | 0.48–2.14 |
Underlying Illnesses | ||||||||
Diabetes Mellitus | 128 | 61 | 1.41 | 1.01–1.99* | 88 | 23 | 1.83 | 1.02–3.29* |
Chronic Renal Failure | 18 | 10 | 1.37 | 0.88–2.14 | 10 | 5 | 2.77 | 1.39–5.54* |
Chronic Lung Disease | 3 | 2 | 1.61 | 0.71–3.63 | 3 | 0 | 0 | NA |
HIV/AIDs | 3 | 1 | 0.79 | 0.16–3.97 | 3 | 1 | 1.71 | 0.34–8.70 |
Immunocompromised States | 5 | 2 | 0.96 | 0.32–2.83 | 2 | 0 | 0 | NA |
Other Diseases | 83 | 30 | 0.80 | 0.57–1.12 | 58 | 14 | 1.36 | 0.76–2.43 |
§ Individuals who were transferred to a different hospital or discharged from the hospital at their own risk were excluded from the analysis as we do not know if they final clinical outcome was death
‡ data shown as case-fatality ratio rather than relative risk ratio
* indicates a p-value <0.05.