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. 2019 Mar 18;15(3):e1007684. doi: 10.1371/journal.ppat.1007684

Fig 8. The involvement of FIP2 in human macrophage biology.

Fig 8

(A) Gene Ontology mapping showing the effect of FIP2 silencing on biological processes in primary human macrophages from 7 donors. (B) Effect of FIP2 silencing on E. coli-stimulated induction of IRF3-target genes. (C) Effect of FIP2 silencing on the E. coli-stimulated induction of a selection of pro-inflammatory genes. Data are median counts with boxed 1.5 IQR 95%. **** (FDR< 0.0001), *** (FDR<0.001), ** (FDR<0.01), * (FDR<0.05). FDR = False Discovery Rate, IQR = Inter Quantile Range.