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. 2019 Mar 28;14(3):e0214191. doi: 10.1371/journal.pone.0214191

Table 2. Patients’ response regarding the medication related quality of life due to polypharmacy.

Items in each domain None of the time N (%) very rarely
N (%)
Rarely
N (%)
Occasionally
N (%)
Frequently
N (%)
All the time N (%) Frequently and All the time % (95% CI)
A. Role limitations due to medication–The domain mean score ± SD (range)2.9 ±1.02
1. Cut down the amount of time you spent on work or daily activities 7(4.7) 24(16) 6(17.3) 42(28) 40(26.7) 11(7.3) 34.0%(26–42)
2. Accomplish the work less than you would like 6 (4) 17 (11.3) 33(22) 46(30.7) 41(27.3) 7(4.7) 32.0% (24–40)
3. Were limited in the work or other daily activities 2(1.3) 18 (12) 27 (18) 40 (26.7) 49(32.7) 14(9.3) 42.0% (34–50)
4. Took extra effort or had difficulty performing the work or daily activities 6 (4) 12 (8) 29 (19.3) 39 (26) 51(34) 13 (8.7) 42.7% (35–51)
5. Interfered with your social activities with family or friends 3 (2) 20 (13.3) 31 (20.7) 47 (31.3) 40 (26.7) 9 (6) 32.7% (25–40)
6. Interfered with you recreational activities, such as exercise or watching TV 2 (1.3) 20 (13.3) 31 (20,7) 45 (30) 45 (30) 7 (4.7) 34.7% (27–42)
B. Self-control- The domain mean score ± SD (range) 3.2±0.84
7. Felt frustrated or down-hearted 3 (2) 14 (9.3) 14 (9.3) 46 (30.7) 57 (38) 16 (10.7) 48.7% (41–57)
8. Thought of yourself as a burden to others 5 (3.3) 7 (4.7) 16 (19.7) 27 (18) 56(37.3) 39 (26) 63.3% (56–71)
9. Worried about disappointing others 2(1.3) 5(3.3) 17(11.3) 35(23.3) 47(31.3) 44(29.4) 60.7% (53–69)
10. Had to cancel scheduled appointments or meetings 4 (2.7) 18 (12) 44 (29.3) 46 (30.7) 28 (18.7) 10 (6.7) 25.3% (18–32)
11. Did not do work or other activities as a result of medication problems 3 (2) 16 (10.7) 35 (23.3) 60 (40) 29 (19.3) 7 (4.7) 24.0% (17–31)
C. Vitality -The domain mean score+ SD (range)- 3.2±0.86
12. Had difficulty focusing on the task at hand or daily activities 4 (2.7) 8 (5.3) 39 (26) 51 (34) 44 (29.3) 4 (2.7) 32.0% (24–40)
13. Had difficulty performing the work or daily activities as a result of feeling worn out 2 (1.3) 7 (4.7) 28 (18.7) 50 (33.3) 53 (35.3) 10 (6.7) 42.0% (34–50)
14. Reduced the number of days feeling full of pep - 13 (8.7) 10 (6.7) 30 (20) 78 (52) 19 (12.7) 64.7% (57–72)

Note: During response for each question, 0 points for “none of the time” whereas 5 points for “All of the time” has been given. The median was the same for all 14 questions (i.e., Median = 3 or occasional). Confidence interval with 95% was computed to the merged response of frequently and all of the time response.