. Author manuscript; available in PMC: 2019 Dec 15.

Published in final edited form as: Bioorg Med Chem Lett. 2018 Oct 24;28(23-24):3652–3657. doi: 10.1016/j.bmcl.2018.10.036

Table 3.

Binding activity (Ki, nm) of penfluridol and its analogs at dopamine receptor subtypes. Data represent mean inhibition (n = 4). NA - not active; ND - not determined.

	D1	D2	D3	D4	D5
PFL	147	159	136	10,000	125
11a	300	148	474	25	437
8a	798	194	209	385	529
6	ND	317	552	1643	ND
11b	10,000	550	782	10,000	744
8b	135	38	62	58	121
8c	10,000	417	437	459	623
13	ND	460	ND	132	ND