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. 2019 Mar 28;2019(3):CD007506. doi: 10.1002/14651858.CD007506.pub4

Gaeini 2012.

Methods Study design: randomised controlled trial
Duration: 12 weeks
Power calculation: not known
Participants Number of participants: N = 40 randomised (n = 20 lean, n = 20 obese)
Inclusion criteria: PCOS, age 18 to 50 years, sedentary lifestyle (no regular exercise during the usual week), ability to come to study exercise facility for monitored exercise, agreement to maintain current weight/dietary patterns for study
Exclusion criteria: patients undergoing treatment for menstrual disorders; antiepileptic drugs; contraceptives; pregnancy or weight loss drugs; those with hepatitis; pulmonary‐cardiac disorders; diabetes; pregnancy; hypo‐and hyperthyroidism Cushing's syndrome and adrenal hyperplasia
Medication use pre and during study: as per exclusion criteria
Groups comparable at study commencement: not known
Participants actively seeking pregnancy at study commencement: not known
n = 20 obese PCOS and 20 lean PCOS
Exclusion criteria: medication for irregular menstruation, epilepsy, use of contraceptive pills, ovulation stimulators, medication for hepatitis, medication for the treatment of coronary and respiratory disease, diabetes, pregnancy, medication for treatment of hypo and hyperthyroid, abnormal TSH, Cushing syndrome, androgen‐producing tumours and adrenal hyperplasia
Interventions Comparison: 2 arms
a) Intervention: aerobic exercise for 12 weeks, 3 sessions per week with intensity 65% to 80% of maximal heart rate for 25 to 30 minutes of aerobic exercise
b) Control: no intervention
Compliance with intervention: not known
Outcomes Measurements: before and after
Endocrine: testosterone (data awaiting clarification from translators)
Anthropometric: BMI (data awaiting clarification from translators)
Notes Location: Iran
Funding: not known

BMI: body mass index; PCOS: polycystic ovary syndrome; TSH: thyroid‐stimulating hormone