Gaeini 2012.
Methods |
Study design: randomised controlled trial Duration: 12 weeks Power calculation: not known |
Participants |
Number of participants: N = 40 randomised (n = 20 lean, n = 20 obese) Inclusion criteria: PCOS, age 18 to 50 years, sedentary lifestyle (no regular exercise during the usual week), ability to come to study exercise facility for monitored exercise, agreement to maintain current weight/dietary patterns for study Exclusion criteria: patients undergoing treatment for menstrual disorders; antiepileptic drugs; contraceptives; pregnancy or weight loss drugs; those with hepatitis; pulmonary‐cardiac disorders; diabetes; pregnancy; hypo‐and hyperthyroidism Cushing's syndrome and adrenal hyperplasia Medication use pre and during study: as per exclusion criteria Groups comparable at study commencement: not known Participants actively seeking pregnancy at study commencement: not known n = 20 obese PCOS and 20 lean PCOS Exclusion criteria: medication for irregular menstruation, epilepsy, use of contraceptive pills, ovulation stimulators, medication for hepatitis, medication for the treatment of coronary and respiratory disease, diabetes, pregnancy, medication for treatment of hypo and hyperthyroid, abnormal TSH, Cushing syndrome, androgen‐producing tumours and adrenal hyperplasia |
Interventions | Comparison: 2 arms a) Intervention: aerobic exercise for 12 weeks, 3 sessions per week with intensity 65% to 80% of maximal heart rate for 25 to 30 minutes of aerobic exercise b) Control: no intervention Compliance with intervention: not known |
Outcomes |
Measurements: before and after Endocrine: testosterone (data awaiting clarification from translators) Anthropometric: BMI (data awaiting clarification from translators) |
Notes |
Location: Iran Funding: not known |
BMI: body mass index; PCOS: polycystic ovary syndrome; TSH: thyroid‐stimulating hormone