Table 3.

Correlation between serum HBV RNA and serum HBsAg

No. of subjects	Correlation				References
	Before treatment	P values	on treatment	P values
47	n/ac	n/ac	C RNAd: >1 year: r=0.665	<0.001	[21]
62	flRNAa: r=0.4	n/ac	3rd month: flRNAa: r=0.39	n/ac	[32]
	trRNAb: r=0.37	n/ac	trRNAb: r=0.34	n/ac
	n/ac	n/ac	6th month: flRNAa: r=0.36	n/ac
	n/ac	n/ac	trRNAb: r=0.31	n/ac
52	n/ac	n/ac	C RNAd: 3rd month: R 2=0.407	n/ac	[41]
86	PreC-C RNAd: HBeAg(+):moderate	n/ac	n/ac	n/ac	[20]
	HBeAg(−):no correlation	n/ac	n/ac	n/ac
102	C RNAd: r=0.703	<0.001	n/ac	n/ac	[52]
84	C RNAd: HBeAg(+): r= 0.537	<0.001	n/ac	n/ac	[37]
	HBeAg(−): r=0.151	0.503	n/ac	n/ac
488	flRNAa: HBeAg(+): r= 0.54	<0.001	n/ac	n/ac	[35]
	HBeAg(−): r=0.19	0.04	n/ac	n/ac
131	flRNAa: r=0.71	<0.05	n/ac	n/ac	[34]

^aflRNA refers to the HBV transcripts terminating at the canonical polyadenylation signal TATAAA motif downstream of HBx ORF;

^btrRNA refers to the HBV transcripts terminating at a cryptic polyadenylation signal, CATAAA, within the HBX ORF;

^cInformation not available.

^dPrimers for quantifying serum HBV RNA target at the X/PreC/C/S region of HBV genome.