Table 2.
Univariate Models |
Extended MV Model |
Reduced MV Model |
|||||
---|---|---|---|---|---|---|---|
β | p-value | β | p-value | β | p-value | ||
Age, per year | −0.0004 | 0.92 | |||||
Male vs female | −0.11 | 0.39 | |||||
Non-Hispanic white | referent | referent | |||||
Non-Hispanic black | 0.34 | 0.029 | 0.20 | 0.24 | |||
Hispanic | 0.17 | 0.14 | 0.064 | 0.63 | |||
Other race | −0.093 | 0.74 | −0.12 | 0.67 | |||
Ever smoking vs. never | −0.023 | 0.82 | |||||
Hypertension, yes v. no | 0.0030 | 0.98 | |||||
BMI, per kg/m2 | 0.018 | 0.042 | 0.014 | 0.10 | 0.015 | 0.068 | |
Diabetes, yes v. no | −0.17 | 0.27 | |||||
Total cholesterol, per mg/dL | −0.0017 | 0.22 | −0.0015 | 0.29 | |||
LDL, per mg/dL | −0.0010 | 0.55 | |||||
HDL, per mg/dL | −0.0016 | 0.56 | |||||
log Triglycerides, per mg/dL | −0.11 | 0.36 | |||||
RA duration (square root), per year | 0.010 | 0.74 | |||||
RF or anti-CCP, yes v. no | 0.011 | 0.93 | |||||
DAS28-CRP>3.2 units | 0.22 | 0.039 | |||||
CDAI >10 units | 0.31 | 0.006 | 0.25 | 0.047 | 0.28 | 0.012 | |
log CRP, per mg/L | 0.0047 | 0.91 | |||||
log IL-6, per pg/mL | 0.015 | 0.74 | |||||
log BNP, per pg/mL | 0.0009 | 0.75 | |||||
AM stiffness (square root), per min | 0.0052 | 0.71 | |||||
HAQ, per unit | 0.11 | 0.099 | −0.019 | 0.79 | |||
Methotrexate, yes v. no | 0.13 | 0.22 | 0.12 | 0.27 | |||
No biologic | referent | referent | referent | ||||
TNF inhibitors | −0.080 | 0.48 | −0.029 | 0.80 | −0.023 | 0.83 | |
Non-TNF biologics | −0.38 | 0.043 | −0.36 | 0.047 | −0.38 | 0.033 | |
Current prednisone, yes v. no | 0.14 | 0.21 | |||||
Current NSAID, yes v. no | 0.067 | 0.52 | |||||
CAC score zero | referent | referent | referent | ||||
CAC score <100 | 0.018 | 0.90 | 0.041 | 0.77 | 0.037 | 0.78 | |
CAC score ≥100 | −0.22 | 0.10 | −0.25 | 0.073 | −0.21 | 0.10 | |
Adjusted R2 | 0.105 | 0.025 | 0.102 | 0.006 |
Legend: Beta coefficients represent the average change in the Log Transformed Myocardial SUVmean per 1-unit higher value of the independent continuous variable of interest or for those with versus those without the independent dichotomous variable of interest. RA: rheumatoid arthritis, RF: rheumatoid factor, CCP: cyclic citrullinated protein antibody, DAS: disease activity score, CDAI: clinical disease activity index HAQ: health assessment questionnaire, AM: morning, CRP: C-reactive protein, IL-6: interleukin 6, CAC: coronary artery calcium