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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: J Neurochem. 2019 Mar 15;149(1):98–110. doi: 10.1111/jnc.14668

Figure 6. Tat activates OL CaMKIIβ in vitro via iGluRs in both immature and mature OLs.

Figure 6.

(A) Western blot results indicate that CaMKIIβ activity was significantly upregulated in both immature and mature OLs after 1 h Tat (100 nM) treatment. (B) Tat-induced upregulation of CaMKIIβ activity can be completely inhibited by MK801, and partially reversed by CNQX (not different from either control or Tat; p=0.113 vs Tat). (* p < 0.05 vs. corresponding vehicle control; # p < 0.05 vs 100 nM Tat.) Results represent N=3 or N=4 independent cultures prepared from mice of different litters.