Table 1.
Selected Demographic Characteristics (%) of Mothers According to Acetaminophen Use During Pregnancy in an Analysis of Attention-Deficit/Hyperactivity Disorder in Offspring, Nurses’ Health Study II, 1993–2005
| Characteristic | Acetaminophen Use at Time of Pregnancy (Yes/No) | |||
|---|---|---|---|---|
| Main Analysis (n = 8,856) | Pregnancy Subset (n = 3,716) | |||
| Yes (n = 1,230) | No (n = 7,626) | Yes (n = 513) | No (n = 3,203) | |
| Maternal age at child’s birth, years | ||||
| <30 | 1.7 | 2.8 | 2.3 | 2.9 |
| 30–34 | 28.3 | 39.0 | 29.0 | 40.2 |
| 35–40 | 50.2 | 43.2 | 47.8 | 43.9 |
| >40 | 19.8 | 15.0 | 20.9 | 13.0 |
| Child’s birth order | ||||
| 1 | 23.4 | 24.8 | 25.7 | 25.7 |
| 2 | 38.0 | 38.3 | 33.3 | 37.4 |
| 3 | 24.7 | 24.8 | 26.1 | 24.5 |
| ≥4 | 13.9 | 12.2 | 14.8 | 12.4 |
| Pregnancy complications | ||||
| Gestational diabetes | 5.9 | 5.1 | 7.2 | 5.6 |
| Preeclampsia | 4.2 | 2.8 | 3.9 | 2.6 |
| Maternal use of acetaminophen | ||||
| Before pregnancy | 41.8 | 12.2 | 45.2 | 11.3 |
| After pregnancy | 51.0 | 18.1 | 52.4 | 18.1 |
| Maternal medication use at time of pregnancy | ||||
| Aspirin | 6.7 | 2.1 | 5.3 | 2.6 |
| Other NSAIDs | 37.9 | 5.2 | 31.6 | 3.0 |
| Maternal diagnosis of chronic illness | ||||
| Rheumatoid arthritis | 3.2 | 1.6 | 3.5 | 1.4 |
| Depression | 25.2 | 16.0 | 26.1 | 15.6 |
| Migraine | 29.8 | 13.6 | 31.2 | 12.9 |
| Maternal lifestyle during pregnancya | ||||
| Cigarette smoking | 7.1 | 4.4 | 7.9 | 4.2 |
| Alcohol drinking | 8.0 | 6.5 | 8.7 | 6.5 |
| Annual household incomea | ||||
| <$50,000 | 15.4 | 12.6 | 15.0 | 12.7 |
| $50,000–$100,000 | 25.3 | 24.1 | 28.9 | 24.0 |
| >$100,000 | 59.3 | 63.4 | 56.1 | 63.3 |
Abbreviation: NSAIDs, nonsteroidal antiinflammatory drugs.
a Information on these factors was available for approximately 75% of the participants.