Table 1.
LQAS Definition, % | Required Sample Size, No. | Sensitivitya, % | Specificityb, % |
---|---|---|---|
2–10c | 76 | 100.0 | 44.1 |
5–20 | 44 | 99.9 | 85.0 |
10–20 | 112 | 100.0 | 98.9 |
10–30 | 37 | 99.6 | 85.2 |
20–50 | 23 | 98.8 | 80.7 |
30–50 | 53 | 99.9 | 87.1 |
Abbreviations: AMR, antimicrobial resistance; LQAS, lot quality assurance sampling.
a Percentage of draws accurately classified as “high resistance.”
b Percentage of draws accurately classified as “low resistance.”
c The upper value indicates the upper threshold of resistance prevalence above which an antibiotic should not be used for the empirical treatment of patients suspected of a urinary tract infection. The lower and upper thresholds together indicate the range of the true but unknown AMR prevalence in which misclassification is allowed to occur.