Table 3.
Expression of genes grouped according to biological role.
| Protein Name | Description | Fold-change | |
|---|---|---|---|
| Microarray | qRT-PCR | ||
| APOPTOSIS | |||
| Extrinsic pathway | |||
| CFLAR | CASP8 and FADD-like apoptosis regulator | −1.13550 | |
| FAS | Fas cell surface death receptor | 0.363 | |
| FASTK | Fas-activated serine/threonine kinase | −0.871 | |
| IFI27 | Interferon alpha-inducible protein 27, mitochondrial | −1.81924 | |
| NFKB1 | Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | −0.858 | −0.76844 |
| NFKB2 | Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.465 | |
| Intrinsic pathway | |||
| BAX | BCL2-associated X protein | −0.578 | −1.29834 |
| BCL2 | BCL2-like 2 | 0.295 | 1.84890 |
| Caspase 9 | Caspase 9, apoptosis-related cysteine peptidase | −0.321 | −2.43964 |
| DIFFERENTIATION | |||
| APCS | Serum amyloid P-component | −0.481 | 1.04006 |
| CD81 | CD81 antigen | −0.797 | |
| IGHM | Ig mu chain C region | −1.012 | |
| LMNA | Prelamin-A/C | −0.497 | −0.30779 |
| POU5F1 | POU domain, class 5, transcription factor 1 | −0.661 | |
| RPS19 | 40 S ribosomal protein S19 | −0.756 | −1.01396 |
| RUNX3 | Runt-related transcription factor 3 | −0.486 | |
| ONCOGENES/TUMOR SUPPRESSORS | |||
| ATF3 | Cyclic AMP-dependent transcription factor ATF-3 | −7.76328 | |
| BRCA1 | Breast cancer 1, early onset | −0.492 | |
| CDKN1A | Cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.411 | 1.47768 |
| CDKN1C | Cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 0.393 | 0.47853 |
| CDKN2A | Cyclin-dependent kinase inhibitor 2A | −0.512 | |
| CDKN2B | Cyclin-dependent kinase 4 inhibitor B | −2.93494 | |
| EP300 | E1A binding protein p300 | −0.772 | |
| IRF7 | Interferon regulatory factor 7 | −0.772 | |
| JUN | Jun proto-oncogene | 0.397 | 0.12186 |
| RB1 | Retinoblastoma 1 | −0.497 | −1.03288 |
| SIGNALLING | |||
| GNAS | GNAS complex locus | 0.308 | |
| HSPA8 | Heat shock 70 kDa protein 8 | 0.441 | 2.33486 |
| IFNGR1 | Interferon gamma receptor 1 | 0.523 | |
| MAPK10 | Mitogen-activated protein kinase 10 | 0.401 | |
| MAPK3 | Mitogen-activated protein kinase 3 | −0.516 | −1.03526 |
| S100A4 | S100 calcium binding protein A4 | 0.310 | |
| S100A6 | S100 calcium binding protein A6 | −1.444 | |
| S100A8 | S100 calcium binding protein A8 | 0.382 | |
| S100A9 | S100 calcium binding protein A9 | −0.733 | |
| SOCS1 | Suppressor of cytokine signalling 1 | −0.932 | |
| VEGFC | Vascular endothelial growth factor C | 0.458 | |
| CELL CYCLE | |||
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | 0.489 | |
| CCNA2 | Cyclin-A2 | 0.745 | 3.96320 |
| CCNB1 | Cyclin B1 | 0.448 | |
| CD72 | CD72 molecule | 0.442 | |
| CDKN1C | Cyclin-dependent kinase inhibitor 1C | 0.393 | |
| GAS1 | Growth arrest-specific 1 | 0.403 | |
| TRANSLATION INITIATION | |||
| EEF1A1 | Elongation factor 1-alpha 1 | −0.422 | −1.37554 |
| EIF2B1 | Translation initiation factor eIF-2B subunit alpha | 0.490 | 1.10445 |
| EIF3B | Eukaryotic translation initiation factor 3 subunit B | −0.974 | |
| EIF3I | Eukaryotic translation initiation factor 3 subunit I | −0.657 | |
| EIF4E | Eukaryotic translation initiation factor 4E | 2.20381 | |
| IMPDH | Inosine-5′-monophosphate dehydrogenase 2 | 1.378724 | |