Table 1.
Measure | VLBW assessed on MRI (N = 150) | VLBW not assessed on MRI (N = 173) | Pa | Controls (N = 50) | Pb |
---|---|---|---|---|---|
Mean (SD) age at scan | 28.5 (1.2) | – | – | 27.7 (0.5) | <0.001 |
% (n) Male | 41.3 (62) | 52.0 (90) | 0.055 | 40.0 (20) | 0.87 |
% (n) Māori/Pacific Island ethnicity | 28.7 (43) | 34.7 (60) | 0.25 | 18.0 (9) | 0.14 |
Mean (SD) birthweight (g) | 1077 (238) | 1213 (215) | <0.001 | ||
% (n) < 1000 g | 38.0 (57) | 15.6 (27) | <0.001 | ||
Mean (SD) gestation (weeks) | 28.8 (2.6) | 29.6 (2.3) | 0.002 | ||
% (n) < 28 weeks gestation | 35.3 (53) | 15.6 (27) | <0.001 | ||
Mean (SD) Apgar 5 min | 7.8 (1.9) | 8.0 (1.7) | 0.51 | ||
% (n) SGA | 30.7 (46) | 27.2 (47) | 0.49 | ||
% (n) Vaginal delivery | 43.8 (64) | 40.1 (69) | 0.5 | ||
% (n) Sepsis | 20.7 (31) | 26.7 (46) | 0.2 | ||
% (n) ANS | 54.7 (82) | 59.5 (103) | 0.38 | ||
% (n) RDS | 56.7 (85) | 56.1 (97) | 0.91 | ||
% (n) BPD | 20.7 (31) | 21.4 (37) | 0.87 | ||
% (n) ROP | 25.0 (36) | 17.4 (27) | 0.11 | ||
% (n) Any neurosensory disability (age 7–8 years) | 16.6 (24) | 33.1 (50) | 0.001 | ||
% (n) Mod/severe disability (age 7–8 years) | 4.1 (6) | 13.9 (21) | 0.004 |
SGA: small for gestational age (birthweight <10% centile), RDS: respiratory distress syndrome, BPD: bronchopulmonary dysplasia (oxygen requirement at 36 weeks post-menstrual age), ANS: antenatal corticosteroids, ROP: retinopathy of prematurity. Moderate or severe disability at 7–8 years of age was defined as cerebral palsy in non-ambulant children or in ambulant children causing considerable limitation of movement; bilateral sensorineural deafness requiring hearing aids; bilateral blindness; or an IQ score of >2 SD below the test mean (<70) on the Revised Wechsler Intelligence Scale for Children (WISC-R). Any neurosensory disability at 7–8 years of age also included cerebral palsy with only minor limitation of movement and mild cognitive impairment (IQ 1-2 SD below the mean).
Comparisons of VLBW assessed and not assessed by t-test or chi square.
Comparisons of VLBW assessed and Controls by t-test or chi square.