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. 2019 Mar 15;22:101780. doi: 10.1016/j.nicl.2019.101780

Table 1.

Comparison of demographic and perinatal characteristics of the surviving VLBW cohort who were assessed on MRI with those not assessed and with controls.

Measure VLBW assessed on MRI (N = 150) VLBW not assessed on MRI (N = 173) Pa Controls (N = 50) Pb
Mean (SD) age at scan 28.5 (1.2) 27.7 (0.5) <0.001
% (n) Male 41.3 (62) 52.0 (90) 0.055 40.0 (20) 0.87
% (n) Māori/Pacific Island ethnicity 28.7 (43) 34.7 (60) 0.25 18.0 (9) 0.14
Mean (SD) birthweight (g) 1077 (238) 1213 (215) <0.001
% (n) < 1000 g 38.0 (57) 15.6 (27) <0.001
Mean (SD) gestation (weeks) 28.8 (2.6) 29.6 (2.3) 0.002
% (n) < 28 weeks gestation 35.3 (53) 15.6 (27) <0.001
Mean (SD) Apgar 5 min 7.8 (1.9) 8.0 (1.7) 0.51
% (n) SGA 30.7 (46) 27.2 (47) 0.49
% (n) Vaginal delivery 43.8 (64) 40.1 (69) 0.5
% (n) Sepsis 20.7 (31) 26.7 (46) 0.2
% (n) ANS 54.7 (82) 59.5 (103) 0.38
% (n) RDS 56.7 (85) 56.1 (97) 0.91
% (n) BPD 20.7 (31) 21.4 (37) 0.87
% (n) ROP 25.0 (36) 17.4 (27) 0.11
% (n) Any neurosensory disability (age 7–8 years) 16.6 (24) 33.1 (50) 0.001
% (n) Mod/severe disability (age 7–8 years) 4.1 (6) 13.9 (21) 0.004

SGA: small for gestational age (birthweight <10% centile), RDS: respiratory distress syndrome, BPD: bronchopulmonary dysplasia (oxygen requirement at 36 weeks post-menstrual age), ANS: antenatal corticosteroids, ROP: retinopathy of prematurity. Moderate or severe disability at 7–8 years of age was defined as cerebral palsy in non-ambulant children or in ambulant children causing considerable limitation of movement; bilateral sensorineural deafness requiring hearing aids; bilateral blindness; or an IQ score of >2 SD below the test mean (<70) on the Revised Wechsler Intelligence Scale for Children (WISC-R). Any neurosensory disability at 7–8 years of age also included cerebral palsy with only minor limitation of movement and mild cognitive impairment (IQ 1-2 SD below the mean).

a

Comparisons of VLBW assessed and not assessed by t-test or chi square.

b

Comparisons of VLBW assessed and Controls by t-test or chi square.