Table 6.

Aromatic interactions in GaTRiC and S. cerevisiae TRiC

Interactions	TRiC subunits	Domain	Organism
			G. antarctica	S. cerevisiae
Aromatic dimers	α	Apical	None	Phe 350-Tyr 354
		Intermediate	None	Phe 60-Tyr 393
		Equatorial	Tyr 129-Phe 449 Tyr 139-Tyr 430 Phe 175-Phe 176 Tyr 478- Phe 496	Phe 129-Phe 451 Phe 175-Phe 176 Tyr 432-Phe 436 Tyr 480-Tyr 497 Tyr 497-Tyr 500
	β	Apical, Intermediate, Equatorial	None	None
	δ	Apical, Intermediate, Equatorial	None	None
Aromatic-sulfur	α	Apical	None	Phe 366- Cys 371
		Intermediate	None	Phe 60-Met 52
		Equatorial	Phe 176- Met 179	Phe 176-Met 179
	β	Apical, Intermediate, Equatorial	None	None
	δ	Apical, Intermediate, Equatorial	None	None
Cation-Pi	α	Apical	Tyr 218-Lys 220	Phe 366-Lys 211 Phe 366-Arg 388
		Intermediate	None	None
		Equatorial	Tyr 497-Arg 495	Phe 14-Arg 9
	β	Apical	Phe 311-Arg 287 Tyr 491- Arg 399 Tyr 491- Arg 495	Phe 279-Lys 336 Phe 284-Arg 316 Phe 329-Lys 270
		Intermediate	Tyr 207-Arg 370	Phe 212-Arg 316 Phe 212-Lys 355
		Equatorial	Phe 23-Arg 19	Phe 23-Arg 19 Tyr 464-Arg 460 Tyr 491-Arg 399
	δ	Apical	Phe 243-Lys 249 Tyr 308-Arg 272 Phe 327-Arg 199	Phe 243- Lys 249 Tyr 308-Arg 272 Phe 327- Arg 199
		Equatorial	Tyr 431-Lys 134	Phe 15-Arg 13 Phe 15-Arg 531 Phe 443-Lys 134