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Sirt3 regulates Fis1 via the JNK signaling pathway. a–f Western blotting was used to analyze p-JNK and Fis1 expression. The JNK blocker SP600125 was used to prevent JNK activation in Sirt3-deleted cells. g–j Immunofluorescence assay for Fis1. The relative fluorescence intensity of Fis1 was measured. *p < 0.05 vs. si-ctrl (control siRNA); #p < 0.05 vs. si1-sirt3 (Sirt3 siRNA1)
