Table 4.
Baseline characteristics according to the number of mature oocytes retrieved (≥ 10 vs < 10) in the whole cohort and in the subgroup of women undergoing proper random start
| Characteristics | Whole cohort | Proper random start | ||||
|---|---|---|---|---|---|---|
| ≥ 10 | < 10 | p | ≥ 10 | < 10 | p | |
| Number | 35 | 37 | 25 | 27 | ||
| Age (years) | 30.1 ± 5.1 | 32.6 ± 5.8 | 0.06 | 30.2 ± 4.6 | 33.6 ± 5.5 | 0.02 |
| BMI (kg/m2) | 22.4 ± 3.9 | 21.0 ± 3.2 | 0.09 | 22.3 ± 3.7 | 20.9 ± 3.0 | 0.14 |
| Previous deliveries | 4 (11%) | 3 (8%) | 0.71 | 2 (8%) | 3 (11%) | 1.00 |
| Menstrual cycle duration (days) | 0.30 | 0.31 | ||||
| 24–27 | 3 (9%) | 7 (19%) | 2 (8%) | 5 (19%) | ||
| 28–32 | 25 (71%) | 26 (70%) | 17 (68%) | 19 (70%) | ||
| > 32 | 7 (20%) | 4 (11%) | 6 (24%) | 3 (11%) | ||
| Serum AMH (ng/ml) | 3.7 (2.2–5.2) | 1.4 (0.6–2.6) | < 0.001 | 3.7 (2.3–5.0) | 1.4 (0.6–1.9) | < 0.001 |
| Total AFC | 23.5 ± 11.0 | 14.1 ± 8.1 | < 0.001 | 24.9 ± 12.0 | 14.4 ± 7.8 | < 0.001 |
| Indication to oocyte cryopreservation | 0.73 | 0.98 | ||||
| Breast cancer | 20 (57%) | 22 (60%) | 15 (60%) | 17 (63%) | ||
| Lymphoma | 11 (31%) | 9 (24%) | 7 (28%) | 7 (26%) | ||
| Others | 4 (11%) | 6 (16%) | 3 (12%) | 3 (11%) | ||
| Ovarian cysts | 2 (6%) | 2 (5%) | 1.00 | 1 (4%) | 2 (7%) | 1.00 |
| Cycle phase at referral | 0.45 | 1.00 | ||||
| Estroprogestins | 2 (6%) | 4 (11%) | 0 (0%) | 0 (0%) | ||
| Follicular phase | 19 (54%) | 15 (40%) | 11 (44%) | 11 (41%) | ||
| Luteal phase | 14 (40%) | 18 (49%) | 14 (56%) | 16 (59%) | ||
| Canceled cycles (poor response) | 0 (0%) | 3 (8%) | 0.24 | 0 (0%) | 3 (11%) | 0.24 |
| Drugs used a | ||||||
| Corrifollitropin 100–150 mcg | 35 (100%) | 34 (100%) | 25 (100%) | 24 (100%) | ||
| Total dose of recombinant FSH (IU) | 1423 ± 1092 | 1924 ± 1109 | 0.10 | 1530 ± 1198 | 2038 ± 1175 | 0.18 |
| Total N of GnRH antagonist ampoules | 5.6 ± 1.2 | 5.0 ± 1.4 | 0.06 | 5.8 ± 1.1 | 5.0 ± 1.5 | 0.05 |
| Duration of stimulation (days)a | 11.3 ± 1.5 | 11.6 ± 2.1 | 0.49 | 11.4 ± 1.2 | 11.7 ± 2.2 | 0.49 |
| N of developed follicles (diameter ≥ 11 mm)a | 25.6 ± 9.9 | 13.1 ± 5.2 | < 0.001 | 26.4 ± 10.0 | 12.9 ± 5.1 | < 0.001 |
| N of oocytes retrieved | 21.8 ± 8.1 | 7.5 ± 4.6 | < 0.001 | 22.8 ± 7.7 | 7.2 ± 4.8 | < 0.001 |
| N of mature oocytes retrieved (frozen) | 16.9 ± 6.3 | 4.6 ± 3.1 | < 0.001 | 17.8 ± 5.9 | 4.6 ± 3.2 | < 0.001 |
aExcluding canceled cycles