Table 2. Predictability for severe asthma by univariate and multivariate logistic regression analyses.
| Variable | Univariate | Multivariate | ||
|---|---|---|---|---|
| OR (95% CI) | P value | OR (95% CI) | P value | |
| Duration of asthma | 1.016 (0.995–1.038) | 0.131 | - | - |
| Total IgE (IU/L) | 1.000 (1.000–1.000) | 0.694 | - | - |
| Total eosinophil count (/uL) | 1.000 (1.000–1.000) | 0.116 | - | - |
| Sputum eosinophil count (%) | 1.004 (0.998–1.011) | 0.207 | - | - |
| Sputum neutrophil count (%) | 0.998 (0.991–1.005) | 0.586 | - | - |
| Serum ECP (µg/L) | 1.007 (1.002–1.011) | 0.002 | - | - |
| Serum periostin (ng/mL) | 1.008 (1.003–1.013) | 0.001 | - | - |
| Serum EDN (MBL) (ng/mL) | 1.007 (1.001–1.013) | 0.025 | - | - |
| Serum EDN (K-EDN) (ng/mL) | 1.003 (1.001–1.006) | 0.003 | 1.004 (1.002–1.007) | 0.003 |
CI, confidence interval; IgE, immunoglobulin E; ECP, eosinophil cationic protein; EDN, eosinophil-derived neurotoxin; ELISA, enzyme-linked immunosorbent assay; Serum EDN (MBL), serum EDN levels measured by ELISA kit of MBL; Serum EDN (K-EDN), serum EDN levels measured by ELISA kit of K-EDN; OR, odds ratio.