Table 2. Comparison of TAC trough levels between BPAR and non-BPAR groups.
TAC groups | Non-BPAR (No.) | BPAR (No.) | P value | |
---|---|---|---|---|
Total number of BPAR | 11 | |||
TAC trough level, ng/mL | ||||
0–2 months | 7.1 ± 1.8 (276) | 7.0 ± 4.9 (2) | 0.995 | |
3–6 months | 6.1 ± 1.7 (270) | 5.6 ± 2.9 (6) | 0.730 | |
7–12 months | 5.7 ± 1.6 (220) | 3.5 ± 0.9 (3) | 0.023 (PS = 0.76) | |
TAC CV, % | ||||
0–2 months | 31.4 ± 16.5 (276) | 31.2 ± 23.3 (2) | 0.990 | |
3–6 months | 29.1 ± 28.4 (270) | 27.8 ± 22.5 (6) | 0.917 | |
7–12 months | 28.3 ± 14.2 (220) | 67.9 ± 24.2 (3) | < 0.001 (PS = 0.99) | |
Average number of TAC trough level measurement | ||||
0–2 months | 5 | 4 | - | |
3–6 months | 4 | 2.8 ± 0.4 | 0.001 | |
7–12 months | 6 | 4.0 ± 1.0 | 0.074 |
Values are shown as mean ± standard deviation.
BPAR = biopsy-proven acute rejection, TAC = tacrolimus, CV = coefficient of variation, PS = power statistic.