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. 2019 Mar 22;9:161. doi: 10.3389/fonc.2019.00161

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Copyright © 2019 Zhou, Zhang, He and Zuo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Alteration frequency of E2F family members and neighbor gene network in OC (cBioPortal). (A) Summary of alterations in E2F family members. (B) OncoPrint visual summary of alteration on a query of E2F family members. (C) Kaplan–Meier plots comparing OS in cases with/without E2F family member gene alterations. (D) Kaplan–Meier plots comparing disease-free survival (DFS) in cases with/without E2F family member alterations. (E) Gene–gene interaction network among E2F family members and 50 most frequently altered neighboring genes.