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. 2019 Mar 22;9:161. doi: 10.3389/fonc.2019.00161

Table 2.

The GO function enrichment analysis of E2F family members and neighbor genes in OC (GeneMANIA).

GO Category Description Count % Log10(P) Log10(q)
GO:0000082 GO biological processes G1/S transition of mitotic cell cycle 20 35.09 −24.16 −19.82
GO:0070317 GO biological processes Negative regulation of G0 to G1 transition 8 14.04 −13.25 −10.65
GO:0008285 GO biological processes Negative regulation of cell proliferation 17 29.82 −11.84 −9.31
GO:0071897 GO biological processes DNA biosynthetic process 10 17.54 −10.36 −7.85
GO:0006260 GO biological processes DNA replication 10 17.54 −9.09 −6.60
GO:0000723 GO biological processes Telomere maintenance 8 14.04 −8.35 −5.89
GO:0045596 GO biological processes Negative regulation of cell differentiation 13 22.81 −7.90 −5.48
GO:0071930 GO biological processes Regulation of transcription involved in G1/S transition of mitotic cell cycle 3 5.26 −7.85 −5.44
GO:0072332 GO Biological processes Intrinsic apoptotic signaling pathway by p53 class mediator 6 10.53 −7.53 −5.13
GO:0001889 GO biological processes Liver development 7 12.28 −7.38 −5.01
GO:0097190 GO biological processes Apoptotic signaling pathway 11 19.30 −6.89 −4.57
GO:0000228 GO cellular components Nuclear chromosome 23 40.35 −21.41 −17.68
GO:1990234 GO cellular components Transferase complex 21 36.84 −16.20 −13.23
GO:0070603 GO cellular components SWI/SNF superfamily-type complex 7 12.28 −9.24 −6.74
GO:0016604 GO cellular components Nuclear body 13 22.81 −7.47 −5.08
GO:0000976 GO molecular functions Transcription regulatory region sequence-specific DNA binding 25 43.86 −21.41 −17.68
GO:0003712 GO molecular functions transcription coregulator activity 18 31.58 −15.31 −12.52
GO:1990841 GO molecular functions Promoter-specific chromatin binding 6 10.53 −8.96 −6.48
GO:0001227 GO molecular functions DNA-binding transcription repressor activity, RNA polymerase II-specific 9 15.79 −7.82 −5.40
GO:0001085 GO molecular functions RNA polymerase II transcription factor binding 7 12.28 −7.25 −4.90